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VU 0155041

Cat. No. M7467

All AbMole products are for research use only, cannot be used for human consumption.

VU 0155041 Structure

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Quality Control & Documentation
Biological Activity

VU 0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). Active in in vivo models of Parkinson's disease following i.c.v. administration. Also available as sodium salt (Cat. No. 3311).

Chemical Information
Molecular Weight 316.18
Formula C14H15Cl2NO3
CAS Number 1093757-42-6
Solubility (25°C) 1eq. NaOH 31.62 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chiellini, et al. Chem Biol. A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor.

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