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Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response.
| CAS Number | 2039148-04-2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Jerry C Lee, et al. Clin Cancer Res. Agonizing over the Stimulatory Immune Checkpoint ICOS
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