Free shipping on all orders over $ 500

Vocacapsaicin hydrochloride

Cat. No. M21479
Vocacapsaicin hydrochloride Structure
Synonym:

CA-008 hydrochloride

Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Vocacapsaicin (CA-008) hydrochloride, as a prodrug of capsaicin, is the first non-opioid TRPV1 agonist. Vocacapsaicin hydrochloride provides lasting pain relief.

Chemical Information
Molecular Weight 496.09
Formula C26H42ClN3O4
CAS Number 1931116-92-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Related TRP Channel Products
N-Oleoyl glutamine

N-oleoyl-glutamine is a PM20D1-regulated N-acyl amino acids (NAAs).

N-Oleoyl valine

N-Oleoyl valine is a N-acyl valine compound that acts as a TRPV3 receptor antagonist.

TAT-M2NX

TAT-M2NX (tatM2NX) is a TRPM2 inhibitor with specific neuroprotective activity in male mice.

SOR-C13

SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM.

GsMTx4 TFA

GsMTx4 TFA is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. In addition, GsMTx4 TFA blocks cation-selective stretch-activated channels (SACs) and attenuates lysophosphatidylcholine (LPC)-induced astrocytotoxicity and microglial cell reactivity.

  Catalog
Abmole Inhibitor Catalog




Keywords: Vocacapsaicin hydrochloride, CA-008 hydrochloride supplier, TRP Channel, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.