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Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase.
| Molecular Weight | 165.62 |
| CAS Number | 1391054-02-6 |
| Solubility (25°C) | Water 33.33 mg/mL DMSO 27.5 mg/mL |
| Storage | 2-8°C, sealed |
[2] Muhamad Y Elrashidi, et al. Emerging drugs for the treatment of tobacco dependence: 2014 update
| Related GABA Receptor Products |
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| TPMPA
TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABAC receptor (KB = 2.1 μM), but not to interact with GABAA (KB = 320 μM) or GABAB receptors (EC50 = 500 μM). |
| CI-966
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