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VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor. It has demonstrated sub-micromal IC50s against the HCV replicons of genotype 1a and 1b. It is currently being evaluated for safety/tolerability, pharmacokinetics and anti-viral efficacy in chronically infected HCV patient.?
| Molecular Weight | 497.73 |
| Formula | C26H36KNO4S |
| CAS Number | 1200133-34-1 |
| Form | Solid |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Erik De Clercq. Current race in the development of DAAs (direct-acting antivirals) against HCV
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