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Vasopressin

Cat. No. M11398
Vasopressin  Structure
Size Price Availability Quantity
5mg USD 50  USD50 In stock
10mg USD 80  USD80 In stock
25mg USD 115  USD115 In stock
50mg USD 193  USD193 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Vasopressin is a cyclic nine-peptide synthesized in the hypothalamus center. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by enhancing the stimulating effect of corticotropin-releasing factor. Vasopressin can also act as a neurotransmitter, acting by binding to specific G-protein-coupled receptors.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 1056.22
Formula C46H65N13O12S2
CAS Number 11000-17-2
Purity >99%
Solubility DMSO ≥ 60 mg/mL
Storage at -20°C
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