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UZH1

Cat. No. M13524

All AbMole products are for research use only, cannot be used for human consumption.

UZH1 Structure

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Quality Control & Documentation
Biological Activity

UZH1 is a racemate of UZH1a and UZH1b. UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1b (IC50=28 µM) is essentially inactive. UZH1 can be used for epitranscriptomic modulation of cellular processes. UZH1 has antitumor activity. UZH1 also can be used as a chemical probe for studying METTL3.

Chemical Information
Molecular Weight 558.71
CAS Number 2925713-02-4
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cecilia Herrero, et al. Proc Natl Acad Sci U S A. Connection between water's dynamical and structural properties: Insights from ab initio simulations

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  Catalog
Abmole Inhibitor Catalog




Keywords: UZH1 supplier, METTL3, inhibitors, activators

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