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UNC5293 is a potent and selective inhibitor of MERTK (Ki=190 pM). UNC5293 inhibits MERTK (IC50=0.9 nM) and is more selective for Axl, Tyro3 and Flt3. UNC5293 showed excellent pharmacokinetic properties in mice.
| Molecular Weight | 518.69 |
| Formula | C30H42N6O2 |
| CAS Number | 2226789-82-6 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
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