Certificate of Analysis
| Product Name: | UNC5293 |
| Catalog Number: | M11273 |
| CAS Number: | 2226789-82-6 |
Physical and Chemical Properties
| Formula: | C30H42N6O2 |
| Molecular Weight: | 518.69 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | UNC5293 is a potent and selective inhibitor of MERTK (Ki=190 pM). UNC5293 inhibits MERTK (IC50=0.9 nM) and is more selective for Axl, Tyro3 and Flt3. UNC5293 showed excellent pharmacokinetic properties in mice. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |