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UMK57

Cat. No. M42860

All AbMole products are for research use only, cannot be used for human consumption.

UMK57 Structure

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Quality Control & Documentation
Biological Activity

UMK57 is a small molecule compound that specifically promotes k-MT attachment error correction to inhibit chromosome missegregation.

Chemical Information
Molecular Weight 295.4
Formula C17H17N3S
CAS Number 342595-74-8
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Thomas J Kucharski et al. bioRxiv. An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

[2] Jessica D Warren et al. Methods Cell Biol. A comparative analysis of methods to measure kinetochore-microtubule attachment stability

[3] Bernardo Orr et al. Cell Rep. Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells

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