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UA62784

Cat. No. M8835

All AbMole products are for research use only, cannot be used for human consumption.

UA62784 Structure

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Quality Control & Documentation
Biological Activity

Studies have also reported that UA62784 associates with tubulin at or near the colchicine-binding sites in cells and functions as a cytotoxic, microtubule inhibitor.

Chemical Information
Molecular Weight 353.37
Formula C23H15NO3
CAS Number 313367-92-9
Solubility (25°C) DMSO: ≥2 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Julia Wrtemberger, et al. Growth inhibition associated with disruption of the actin cytoskeleton by Latrunculin A in rhabdomyosarcoma cells

[2] Helder Maiato, et al. Motor-dependent and -independent roles of CENP-E at kinetochores: the cautionary tale of UA62784

[3] Sergey Tcherniuk, et al. UA62784 Is a cytotoxic inhibitor of microtubules, not CENP-E

[4] David Calligaris, et al. Chemical inhibitors: the challenge of finding the right target

[5] Meredith C Henderson, et al. UA62784, a novel inhibitor of centromere protein E kinesin-like protein

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Keywords: UA62784 supplier, inhibitors, activators

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