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U 90042

Cat. No. M7441

All AbMole products are for research use only, cannot be used for human consumption.

U 90042 Structure

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Quality Control & Documentation
Biological Activity

U 90042 is a gABAA receptor ligand that binds with comparable affinities to three receptor subtypes: α1β2γ2, α3β2γ2 and α6β2γ2 (Ki values are 7.8, 9.5 and 11.0 nM respectively). Potentiates GABA-induced chloride currents in α6β2γ2 receptors. Sedative/hypnotic compound.

Chemical Information
Molecular Weight 352.78
Formula C17H13ClN6O
CAS Number 134516-99-7
Solubility (25°C) DMSO 10.58 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Rasmussen and McCann. Pharmacol Ther. Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat.

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Abmole Inhibitor Catalog




Keywords: U 90042 supplier, inhibitors, activators

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