Free shipping on all orders over $ 500

TXA6101

Cat. No. M21096

All AbMole products are for research use only, cannot be used for human consumption.

TXA6101  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

TXA6101 is a filamentous temperature-sensitive mutant Z (FtsZ) protein inhibitor. TXA6101 has an antibacterial activity MIC value of 1 μg/mL against MRSA isolates expressing either G193D or G196S mutant FtsZ, retaining significant activity against the TXA707-resistant FtsZ mutant. It is being developed for use against Gram-negative bacteria.

Chemical Information
Molecular Weight 477.18
Formula C18H10BrF5N2O3
CAS Number 1459695-66-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jesus D Rosado-Lugo, et al. J Antibiot (Tokyo). Evaluation of 2,6-difluoro-3-(oxazol-2-ylmethoxy)benzamide chemotypes as Gram-negative FtsZ inhibitors

[2] Junso Fujita, et al. ACS Chem Biol. Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ

Related Products
DSPE-PEG-FA

DSPE-PEG2K-FA is a PEG derivative containing folic acid. DSPE-PEG2K-FA has a targeting effect and can bind to folic acid receptors in cancer cells. DSPE-PEG2K-FA forms micelles/lipid bilayers and can be used in research on targeted drug delivery systems.

Lifastuzumab

Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody.

GPVI antagonist 1

GPVI antagonist 1 is a glycoprotein VI (GPVI) platelet receptor antagonist. GPVI antagonist 1 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM.

MPSD TFA

MPSD TFA (MARCKS-ED TFA) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition.

4-Nitro-2,1,3-benzoselenadiazole

4-Nitro-2,1,3-benzoselenadiazole is a biochemical material that can be used in scientific research.

  Catalog
Abmole Inhibitor Catalog




Keywords: TXA6101 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.