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Triphenyl phosphate (TPP, triphenyl phosphate) is an organophosphate esters (OPEs), as well as a selective PPARγ regulator, and induces macrophage dysfunction through activation of the TLR4-mediated ERK/NF-κB signaling pathway, which induces apoptosis in mouse hepatocytes. Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NFκB), interleukin-6, and tumor necrosis factor α.
| Molecular Weight | 326.28 |
| Formula | C18H15O4P |
| CAS Number | 115-86-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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