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Trabodenoson

Cat. No. M30772

All AbMole products are for research use only, cannot be used for human consumption.

Trabodenoson Structure
Synonym:

INO-8875

Price and Availability

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Quality Control & Documentation
Biological Activity

Trabodenoson (INO-8875), an adenosine mimetic, is a highly selective Adenosine A1 receptor agonist. Trabodenoson (INO-8875) is used in the study for Primary Open-Angle Glaucoma.

Chemical Information
Molecular Weight 380.36
Formula C15H20N6O6
CAS Number 871108-05-3
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yan Guo, et al. Transl Vis Sci Technol. Topical Trabodenoson Is Neuroprotective in a Rodent Model of Anterior Ischemic Optic Neuropathy (rNAION)

[2] Agne Žiniauskaite, et al. Invest Ophthalmol Vis Sci. Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome

[3] Guorong Li, et al. Invest Ophthalmol Vis Sci. Trabodenoson, an Adenosine Mimetic With A1 Receptor Selectivity Lowers Intraocular Pressure by Increasing Conventional Outflow Facility in Mice

[4] Alan Laties, et al. J Ocul Pharmacol Ther. A Randomized Phase 1 Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Trabodenoson in Healthy Adult Volunteers

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Keywords: Trabodenoson, INO-8875 supplier, Adenosine Receptor, inhibitors, activators

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