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TPX-0046 is a novel RET/SRC inhibitor that is used against RET in Ba/F3 cell proliferation assaysG810R The average IC50 is 17 nM.
| Molecular Weight | 424.43 |
| Formula | C21H21FN6O3 |
| CAS Number | 2359650-19-2 |
| Solubility (25°C) | DMSO ≥ 1 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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