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Toreforant

Cat. No. M40966

All AbMole products are for research use only, cannot be used for human consumption.

Toreforant Structure

Synonym:

JNJ-38518168

Price and Availability

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Quality Control & Documentation

Purity: >99.0%
COA
MSDS

Product Information

Biological Activity

Toreforant is an orally active histamine H4 receptor antagonist that may be used in studies related to psoriasis.

Chemical Information

Molecular Weight	392.54
Formula	C23H32N6
CAS Number	952494-46-1
Storage	-20°C

References

[1] David L Boyle et al. Inflamm Res. Toreforant, an orally active histamine H4-receptor antagonist, in patients with active rheumatoid arthritis despite methotrexate: mechanism of action results from a phase 2, multicenter, randomized, double-blind, placebo-controlled synovial biopsy study

[2] Ellen Frankel et al. J Drugs Dermatol. Efficacy and Safety of Toreforant, a Selective Histamine H4 Receptor Antagonist, for the Treatment of Moderate-to-Severe Plaque Psoriasis: Results from a Phase 2 Multicenter, Randomized, Double-blind, Placebo-controlled Trial

[3] Alexa P Kollmeier et al. Ann Allergy Asthma Immunol. A phase 2a study of toreforant, a histamine H4 receptor antagonist, in eosinophilic asthma

[4] Robin L Thurmond et al. Handb Exp Pharmacol. Clinical Development of Histamine H4 Receptor Antagonists

[5] Robin L Thurmond et al. J Rheumatol. Toreforant, A Histamine H4 Receptor Antagonist, in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: Results of 2 Phase II Studies

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Catalog

Abmole Inhibitor Catalog

Keywords: Toreforant, JNJ-38518168 supplier, Histamine Receptor, inhibitors, activators

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