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TNP is a reversible inositol hexakisphosphate kinase (IP6K) inhibitor (IC50 = 0.47 μM for inhibition of InsP7 formation). Also inhibits inositol 1,4,5-trisphosphate 3-kinase (IP3K) (IC50 = 10.2 μM). Binds to the ATP binding site of IP3K (Ki = 4.3 μM).
| Molecular Weight | 443.38 |
| Formula | C20H16F3N7O2 |
| CAS Number | 519178-28-0 |
| Solubility (25°C) | DMSO 44.34 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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