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TMPPAA

Cat. No. M8626

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TMPPAA Structure

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Quality Control & Documentation
Biological Activity

TMPPAA is an allosteric agonist and positive allosteric modulator (PAM) of 5-HT3 receptor. TMPPAA behaves as both an agonist and a PAM at 5-HT3A receptors, not via binding at the orthosteric site.

Chemical Information
Molecular Weight 247.33
Formula C15H21NO2
CAS Number 844900-50-1
Solubility (25°C) DMSO: 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Agnes Gasiorek, et al. Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors

[2] Hin-Koon Woo, et al. Phosphonium labeling for increasing metabolomic coverage of neutral lipids using electrospray ionization mass spectrometry

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Keywords: TMPPAA supplier, inhibitors, activators

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