All AbMole products are for research use only, cannot be used for human consumption.
Testosterone modulates vascular endothelial cell (EC) growth and platelet aggregation through its direct action on endothelial NO production. Testosterone stimulates NO synthesis via its direct action on ECs. Testosterone involves a nongenomic stimulation of NO synthesis, which depends on calcium influx from the extracellular medium and on MAPK and PKC pathways. Testosterone increases EC growth in bovine aortic and in vein ECs. Testosterone stimulates EC migration. Testosterone stimulates VEGF and NOS expression and promotes capillary formation in the cerebral vascular system. In fact, in bovine aortic ECs, Testosterone and DHEA promote EC proliferation, migration, and vascular tube formation, effects dependent on PTX-sensitive G protein and ERK1/2 activation.
J Ovarian Res. 2024 Nov 15;17(1):223.
Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHA
Testosterone purchased from AbMole
Arch Microbiol. 2024 Sep 11;206(10):401.
The role of male hormones in bacterial infections: enhancing Staphylococcus aureus virulence through testosterone-induced Agr activation
Testosterone purchased from AbMole
J Transl Med. 2023 Feb 18;21(1):129.
Anti-oncogenic effects of dutasteride, a dual 5-alpha reductase inhibitor and a drug for benign prostate hyperplasia, in bladder cancer
Testosterone purchased from AbMole
Cell Commun Signal. 2022 May 9;20(1):61.
Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome
Testosterone purchased from AbMole
J Steroid Biochem Mol Biol. 2013 Nov;138:54-62.
Effect of androgens on different breast cancer cells co-cultured with or without breast adipose fibroblasts
Testosterone purchased from AbMole
| Molecular Weight | 288.42 |
| Formula | C19H28O2 |
| CAS Number | 58-22-0 |
| Solubility (25°C) | 52 mg/mL in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Androgen Receptor Products |
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| LGD-3303
LGD-3303 is a nonsteroidal, nonaromatizable selective androgen receptor ligand that binds to the androgen receptor with high affinity in a radiolabeled to competitive binding assay (Ki=0.9 nM). |
| Ar-V7-IN-1
Ar-V7-IN-1 is a potent inhibitor of Ar-V7. AR-V7 is a hormone-independent splice variant of the androgen receptor. Ar-V7-IN-1 has the potential for the research of various indications such as prostate cancer. |
| SC912
SC912 is a potent and selective AR-V7 inhibitor with IC50 of 0.36 μM. SC912 binds directly to AR-FL and AR-V7 proteins, inhibites nuclear localization and chromatin binding capabilities. SC912 exerts anticancer activity through inhibition of proliferation, induction of cell cycle arrest and apoptosis. |
| A4B17
A4B17 is an androgen receptor N-terminal inhibitor, which can be used for the research of androgen-responsive prostate cancer. |
| AZ'3137
AZ‘3137 is an orally active PROTAC-type androgen receptor (AR) degrader, with a DC50 value of 22 nM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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