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Terlipressin acetate

Cat. No. M11396
Terlipressin acetate Structure
Size Price Availability Quantity
5mg USD 48  USD48 In stock
10mg USD 65  USD65 In stock
25mg USD 120  USD120 In stock
100mg USD 255  USD255 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Terlipressin acetate is a vasopressin analogue and a highly selective vasopressin V1 receptor agonist that reduces visceral blood flow and portal vein pressure and controls acute varicose rupture bleeding. Terlipressin acetate has anti-inflammatory and antioxidant effects and can be used to study hepatorenal syndrome and norepinephrine-resistant septic shock.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 1287.43
Formula C54H78N16O17S2
CAS Number 1884420-36-3
Purity >99%
Solubility DMSO ≥ 60 mg/mL
Storage at -20°C
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Keywords: Terlipressin acetate supplier, Vasopressin Receptor, inhibitors

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