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Teplizumab

Cat. No. M25261

All AbMole products are for research use only, cannot be used for human consumption.

Teplizumab Structure
Synonym:

MGA-031; PRV-031

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Quality Control & Documentation
Biological Activity

Teplizumab (MGA-031) is a Fc receptor non-binding anti-human CD3 monoclonal antibody. Teplizumab reduces the loss of beta-cell function. Teplizumab can be used in the research of type 1 diabetes.

Chemical Information
CAS Number 876387-05-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Susan J Keam. Drugs. Teplizumab: First Approval

[2] No authors listed. Teplizumab

[3] Emily K Sims, et al. Sci Transl Med. Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals

[4] Kevan C Herold, et al. N Engl J Med. An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes

[5] Nicole Sherry, et al. Lancet. Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial

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Keywords: Teplizumab, MGA-031; PRV-031 supplier, inhibitors, activators

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