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TC-SP 14 is a potent and selective S1P1 agonist (EC50 values are 0.042 and 3.47 μM for human S1P1 and S1P3 respectively). Attenuates immune response to antigen challenge and reduces circulating blood lymphocyte counts in a rodent model of delayed-type hypersensitivity. Orally bioavailable.
| Molecular Weight | 450.5 |
| Formula | C25H20F2N2O2S |
| CAS Number | 1257093-40-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 22.52 mg/mL (with gentle warming) |
| Storage | RT, dry |
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