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TC-SP 14

Cat. No. M7398

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TC-SP 14 Structure
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Biological Activity

TC-SP 14 is a potent and selective S1P1 agonist (EC50 values are 0.042 and 3.47 μM for human S1P1 and S1P3 respectively). Attenuates immune response to antigen challenge and reduces circulating blood lymphocyte counts in a rodent model of delayed-type hypersensitivity. Orally bioavailable.

Chemical Information
Molecular Weight 450.5
Formula C25H20F2N2O2S
CAS Number 1257093-40-5
Form Solid
Solubility (25°C) DMSO 22.52 mg/mL (with gentle warming)
Storage RT, dry

[1] Dukes, et al. J Steroid Biochem Mol Biol. The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)-a potent, selective aromatase inhibitor.

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Abmole Inhibitor Catalog

Keywords: TC-SP 14 supplier, S1P Receptor, inhibitors, activators

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