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S1PR1 modulator 1 

Cat. No. M29512

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S1PR1 modulator 1  Structure
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Quality Control & Documentation
Biological Activity

S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4.

Chemical Information
Molecular Weight 408.51
Formula C23H24N2O3S
CAS Number 2328109-05-1
Form Solid
Solubility (25°C) DMSO 50 mg/mL
DMF 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gary Álvarez Bravo, et al. Cells. Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway Modulators, from Current Insights to Future Perspectives

[2] Tamara Pérez-Jeldres, et al. Drugs. Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis

[3] Reshmi Roy, et al. CNS Drugs. Sphingosine 1-Phosphate Receptor Modulators for Multiple Sclerosis

[4] Anja Nitzsche, et al. Circ Res. Endothelial S1P1 Signaling Counteracts Infarct Expansion in Ischemic Stroke

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  Catalog
Abmole Inhibitor Catalog




Keywords: S1PR1 modulator 1  supplier, S1P Receptor, inhibitors, activators

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