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TC-I 2014 is a potent TRPM8 antagonist (IC50 values are 0.8, 3.0 and 4.4 nM for canine, human and rat channels respectively). Exhibits antiallodynic properties in pain models in vivo.
| Molecular Weight | 467.41 |
| Formula | C23H19F6N3O |
| CAS Number | 1221349-53-6 |
| Solubility (25°C) | DMSO 46.74 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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