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TC-G 1001

Cat. No. M7371

All AbMole products are for research use only, cannot be used for human consumption.

TC-G 1001 Structure

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Quality Control & Documentation
Biological Activity

TC-G 1001 is a gPR35 agonist (pEC50 values are 7.59 and 8.36 for β-arrestin and Gαq-i5 Ca2+ assays respectively). TC-G 1001 displays 1000-fold greater potency at human GPR35 receptors relative to mouse and rat GPR35 orthologs in an IP1 accumulation assay. More potent than zaprinast.

Chemical Information
Molecular Weight 342.34
Formula C17H11FN2O3S
CAS Number 494191-73-0
Solubility (25°C) DMSO 3.42 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Slemmon, et al. J Biol Chem. Camstatins are peptide antagonists of calumodulin based upon a conserved structural motif in PEP-19, a neurogranin and neuromodulin J.

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