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TC AC 28 is a high affinity BET bromodomain ligand (Kd values are 40 and 800 nM for Brd2(2) and Brd2(1), respectively). Exhibits 20-fold selectively for the second over the first bromodomain.
| Molecular Weight | 415.44 |
| Formula | C23H21N5O3 |
| CAS Number | 1809296-92-1 |
| Solubility (25°C) | DMSO 2.08 mg/mL (with gentle warming) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Depoortere, et al. Eur J Pharmacol. Antagonistic properties of [Phe3,Leu13]porcine motilin.
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