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tBID

Cat. No. M14891

All AbMole products are for research use only, cannot be used for human consumption.

tBID Structure

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Quality Control & Documentation
Biological Activity

tBID is a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2) with an IC50 of  0.33 µM.

Chemical Information
Molecular Weight 528.78
CAS Number 1639895-85-4
Solubility (25°C) DMSO 26 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jiamiao Lu, et al. In vitro assessment of an engineered tBID-based safety switch system in human T lymphocytes

[2] Hector Flores-Romero, et al. BCL-2-family protein tBID can act as a BAX-like effector of apoptosis

[3] Fabronia Murad, et al. Bcl-xL inhibits tBid and Bax via distinct mechanisms

[4] Marius Meise, et al. Early process development of API applied to poorly water-soluble TBID

[5] Etienne Raemy, et al. Involvement of cardiolipin in tBID-induced activation of BAX during apoptosis

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Keywords: tBID supplier, inhibitors, activators

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