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TB 21007

Cat. No. M7357

All AbMole products are for research use only, cannot be used for human consumption.

TB 21007 Structure

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Quality Control & Documentation
Biological Activity

TB 21007 is a gABAA receptor inverse agonist selective for the α5-subtype (Ki values are 1.6, 16, 20 and 20 nM for α5, α2, α1 and α3 subtypes respectively). Brain penetrant; enhances cognitive performance in rats in the delayed matching-to-place morris water maze test following i.p. administration.

Chemical Information
Molecular Weight 339.5
Formula C15H17NO2S3
CAS Number 207306-50-1
Solubility (25°C) DMSO 33.95 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Brickner, et al. J Med Chem. Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multi-drug-resistant gram-positive bacterial infections.

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