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Tamsulosin hydrochloride

Cat. No. M1889

All AbMole products are for research use only, cannot be used for human consumption.

Tamsulosin hydrochloride Structure
Synonym:

(R)-(-)-YM12617; LY253351

Size Price Availability Quantity
50mg USD 65  USD65 In stock
100mg USD 95  USD95 In stock
200mg USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Tamsulosin is an α1A-blocker (pKi values are 9.97, 9.64 and 8.86 for α1A, α1B and α1D subtypes respectively). Tamsulosin decreases resting maximal urethral pressure with negligable effect on mean arterial blood pressure in vivo.

Chemical Information
Molecular Weight 444.97
Formula C20H28N2O5S.HCl
CAS Number 106463-17-6
Solubility (25°C) DMSO 80 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] A Sebastianelli, et al. Tadalafil Alone or in Combination with Tamsulosin for the Management for LUTS/BPH and ED

[2] Steven A Kaplan, et al. Efficacy and Safety of Mirabegron versus Placebo Add-On Therapy in Men with Overactive Bladder Symptoms Receiving Tamsulosin for Underlying Benign Prostatic Hyperplasia: A Randomized, Phase 4 Study (PLUS)

[3] Andrew C Meltzer, et al. Effect of Tamsulosin on Passage of Symptomatic Ureteral Stones: A Randomized Clinical Trial

[4] Yinghui Duan, et al. Tamsulosin and the risk of dementia in older men with benign prostatic hyperplasia

[5] H L Zhang, et al. Tamsulosin for treatment of lower urinary tract symptoms in women: a systematic review and meta-analysis

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Keywords: Tamsulosin hydrochloride, (R)-(-)-YM12617; LY253351 supplier, Adrenergic Receptor, inhibitors, activators

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