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Talazoparib tosylate (BMN 673 tosylate) is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1.
| Molecular Weight | 552.55 |
| CAS Number | 1373431-65-2 |
| Solubility (25°C) | DMSO ≥ 108 mg/mL |
| Storage | 2-8°C, dry, sealed |
[1] G Guney Eskiler. Drugs Today (Barc). Talazoparib to treat BRCA-positive breast cancer
| Related PARP Products |
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| 2-Methylquinazolin-4-ol
2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with IC50 of 0.20 mM. |
| DPQ
DPQ is a potent PARP-1 inhibitor. |
| OUL232
OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. |
| AZ3391
AZ3391 is a potent inhibitor of PARP. |
| PARP1-IN-5
PARP1-IN-5 is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). |
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