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SYP-5

Cat. No. M8722

All AbMole products are for research use only, cannot be used for human consumption.

SYP-5 Structure

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Quality Control & Documentation
Biological Activity

SYP-5 is potent and selective inhibitor of HIF-1 activity that decreases HIF-1α and HIF-1β protein levels under hypoxic condition. SYP-5 inhibits tumor cell migration and invasion, as well as tumor angiogenesis.

Chemical Information
Molecular Weight 312.38
Formula C18H16O3S
CAS Number 1384268-04-5
Solubility (25°C) DMSO: 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuanyuan Liu, et al. SYP-5 regulates meiotic thermotolerance in Caenorhabditis elegans

[2] Lulu Zheng, et al. An Oxygen-Concentration-Controllable Multiorgan Microfluidic Platform for Studying Hypoxia-Induced Lung Cancer-Liver Metastasis and Screening Drugs

[3] Zhenguo Zhang, et al. Multivalent weak interactions between assembly units drive synaptonemal complex formation

[4] Matthew E Hurlock, et al. Identification of novel synaptonemal complex components in C. elegans

[5] Li-Hui Wang, et al. SYP-5, a novel HIF-1 inhibitor, suppresses tumor cells invasion and angiogenesis

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Keywords: SYP-5 supplier, inhibitors, activators

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