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Suzetrigine (VX-548) is an orally active, highly selective NaV1.8 inhibitor , which can be used in studies related to acute pain and neuralgia.
| Molecular Weight | 473.4 |
| Formula | C21H20F5N3O4 |
| CAS Number | 2649467-58-1 |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Sodium Channel Products |
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AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. |
| Camostat mesylate
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| Clopamide
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