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Sulforhodamine B sodium salt

Cat. No. M11518
Sulforhodamine B sodium salt Structure
Synonym:

Acid Red 52; Kiton Red 620

Size Price Availability Quantity
100mg USD 45  USD45 In stock
1g USD 58  USD58 In stock
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Quality Control & Documentation
Biological Activity

Sulforhodamine B is a water-soluble dye with a maximum excitation/emission wavelength of 565 nm/586 nm, emitting orange-red fluorescence. It is often used to observe the cytoplasm. Store at room temperature away from light.

Chemical Information
Molecular Weight 580.65
Formula C27H29N2NaO7S2
CAS Number 3520-42-1
Solubility (25°C) Water ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Estela Climent, et al. Micromachines (Basel). Loading and Release of Charged and Neutral Fluorescent Dyes into and from Mesoporous Materials: A Key Role for Sensing Applications

[2] Jutharat Waiyawat, et al. J Oral Biosci. Fabrication of calcium phosphate composite polymer/SLS-stabilized emulsion-based bioactive gels and their application for dentine tubule occlusion

[3] Nataliia Hudz, et al. Ceska Slov Farm. Study of biocompatibility of peritoneal dialysis solutions measured as in vitro cells viability

[4] Chong In Shin, et al. Pharmaceutics. Delivery of Niacinamide to the Skin Using Microneedle-Like Particles

[5] Mehdi Rezaee, et al. J Control Release. Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems

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