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STEARDA

Cat. No. M7335

All AbMole products are for research use only, cannot be used for human consumption.

STEARDA Structure

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Quality Control & Documentation
Biological Activity

STEARDA is a endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC50 > 25 μM). However, potentiates TRPV1-mediated effects of NADA in vitro and in vivo; enhances effects on intracellular Ca2+ (EC50 lowered 3-fold) and nociception. Also inhibits arachidonate 5-lipoxygenase (IC50 = 16 nM).

Chemical Information
Molecular Weight 419.64
Formula C26H45NO3
CAS Number 105955-10-0
Solubility (25°C) ethanol 2.1 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chan, et al. Biochem Biophys Res Commun. Identification of a new class of ETA selective endothelin antagonists by pharmacophore directed screening.

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Keywords: STEARDA supplier, inhibitors, activators

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