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SR9186 (ML368) is a potent CYP3A4 inhibitor with IC50 s for inhibition of midazolam → 1′hydroxymidazolam, testosterone → 6β-hydroxytestosterone, and vincristine → vincristine M1 of 9, 4, and 38 nM, respectively. SR-9186 inhibits liver-stage development of P. falciparum to block ivermectin metabolism.
| Molecular Weight | 430.46 |
| Formula | C26H18N6O |
| CAS Number | 1361414-26-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 31.25 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| (3S,5S)-Atorvastatin sodium salt
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Products are for research use only. Not for human use. We do not sell to patients.
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