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SR58611A is a potent, specific b3 adrenergic receptor agonist. The EC50 for reduction of β3-mediated spontaneous motility in rat distal colon sections is 3.5 nM. Minimal anti-depressant efficacious doses for SR58611A are 0.1-0.3 mpk in rodent models.
| Molecular Weight | 440.36 |
| Formula | C22H26ClNO4 · HCl |
| CAS Number | 121524-09-2 |
| Solubility (25°C) | DMSO: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] No authors listed. Drugs R D. SR 58611A: SR 58611
[3] E Nisoli, et al. SR 58611A: a novel thermogenic beta-adrenoceptor agonist
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