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SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. The compound inhibits the activity of p300/CBP, but potentiates p300/CBP-associated factor (PCAF) activity. SPV106 also induces S-phase cell cycle arrest and apoptosis in U937 cells.
| Molecular Weight | 368.55 |
| Formula | C22H40O4 |
| CAS Number | 1036939-38-4 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Francesco Spallotta, et al. Enhancement of lysine acetylation accelerates wound repair
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