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Spiperone

Cat. No. M8188

All AbMole products are for research use only, cannot be used for human consumption.

Spiperone Structure
Synonym:

Spiroperidol

Price and Availability

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Quality Control & Documentation
Biological Activity

Spiperone is a potent dopamine D2, α1B-adrenoceptor, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone has the potential for the research of neurology diseases.

Chemical Information
Molecular Weight 395.47
Formula C23H26FN3O2
CAS Number 749-02-0
Solubility (25°C) DMSO 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Dohyun Im, et al. Structure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone

[2] Crist N Filer, et al. Spiperone: Tritium labelling at high specific activity

[3] Richard A Glennon, et al. Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists

[4] P S Dannies, et al. Spiperone: evidence for uptake into secretory granules

[5] A L Gundlach, et al. 125I-Spiperone: a novel ligand for D2 dopamine receptors

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Keywords: Spiperone, Spiroperidol supplier, Dopamine Receptor, inhibitors, activators

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