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Spiperone hydrochloride

Cat. No. M7320

All AbMole products are for research use only, cannot be used for human consumption.

Spiperone hydrochloride Structure

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Quality Control & Documentation
Biological Activity

Spiperone hydrochloride is a 5-HT2A serotonin and selective D2-like dopamine receptor antagonist (Ki values are 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D2, D3, D4, D1 and D5 receptors respectively). Antipsychotic.

Chemical Information
Molecular Weight 431.94
Formula C23H26FN3O2.HCl
CAS Number 2022-29-9
Solubility (25°C) DMSO 43.19 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lorenzo, et al. Proc Natl Acad Sci USA. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

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