All AbMole products are for research use only, cannot be used for human consumption.
Spermine is a biogenic polyamine formed from spermidine and occurs in almost all tissues. It is essential for both neoplastic and normal tissue growth and is involved in the modulation of calcium-dependent immune processes. Spermine inhibits NOS1 (nNOS). Spermine binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner. Spermine is a GluR inhibitor.
| Molecular Weight | 202.34 |
| Formula | C10H26N4 |
| CAS Number | 71-44-3 |
| Solubility (25°C) | Water ≥ 50 mg/mL |
| Storage | 2-8°C, dry, protect from light, sealed |
[4] Silvia Grancara, et al. Bidirectional fluxes of spermine across the mitochondrial membrane
[5] R Amendola, et al. Spermine metabolism and anticancer therapy
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Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue. |
| PK095
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| Cjoc42
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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