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SN32976

Cat. No. M43387

All AbMole products are for research use only, cannot be used for human consumption.

SN32976 Structure

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Quality Control & Documentation
Biological Activity

SN32976 is a potent and selective class I PI3K and mTOR inhibitor with IC50s of 15.1 nM, 461 nM, 110 nM, 134 nM and 194 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and mTOR, respectively.

Chemical Information
Molecular Weight 581.64
Formula C24H33F2N9O4S
CAS Number 1246202-11-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anna C Giddens et al. Bioorg Med Chem. Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474

[2] Gordon W Rewcastle et al. Oncotarget. Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors

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  Catalog
Abmole Inhibitor Catalog




Keywords: SN32976 supplier, PI3K, inhibitors, activators

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