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SM-7368 is a cell-permeable inhibitor of TNF-α-induced MMP-9 upregulation. Also, SM-7368 strongly inhibits TNF-α-induced NF-kB activity but not AP-1 activity. The compound inhibits the TNF-α-induced invasion of HT1080 human fibrosarcoma cell line.
| Molecular Weight | 328.69 |
| Formula | C10H5ClN4O5S |
| CAS Number | 380623-76-7 |
| Solubility (25°C) | DMSO: 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Melissa J Mulla, et al. Regulation of Nod1 and Nod2 in first trimester trophoblast cells
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