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SKA 31 is a activator of KCa3.1 and KCa2 channels (EC50 values are 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively). Potentiates acetylcholine-induced EDHF-type dilations of mouse carotid arteries and lowers blood pressure in normotensive and hypertensive mice.
| Molecular Weight | 200.26 |
| Formula | C11H8N2S |
| CAS Number | 40172-65-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 20.03 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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