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SID7969543

Cat. No. M8155

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SID7969543 Structure

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Quality Control & Documentation
Biological Activity

SID7969543 is a SF-1 (or NR5A1) inhibitor. The Steroidogenic Factor 1 (SF-1, also known as NR5A1) is a transcription factor belonging to the nuclear receptor superfamily. It plays a central role in sex determination and the formation of steroidogenic tissues during development, and is involved in endocrine function throughout life. It has also been reported to have a potential role in obesity. It has also been observed that an increased concentration of SF-1 causes adrenocortical cell proliferation and cancer.

Chemical Information
Molecular Weight 452.46
Formula C24H24N2O7
CAS Number 868224-64-0
Solubility (25°C) DMSO: ≥10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mawar Karsa, et al. Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia

[2] Franck Madoux, et al. Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening

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  Catalog
Abmole Inhibitor Catalog




Keywords: SID7969543 supplier, inhibitors, activators

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