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Sibeprenlimab

Cat. No. M25112

All AbMole products are for research use only, cannot be used for human consumption.

Sibeprenlimab Structure
Synonym:

VIS649

Size Price Availability Quantity
100ug USD 160  USD160 In stock
1mg USD 250  USD250 In stock
5mg USD 750  USD750 In stock
10mg USD 1200  USD1200 In stock
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Quality Control & Documentation
Biological Activity

Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody. Sibeprenlimab can inhibit APRIL. Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab can be used for the research of IgA nephropathy (IgAN).

Chemical Information
CAS Number 2382896-07-1
Storage Store at -80°C for 2 years.
References

[1] Dita Maixnerova, et al. Expert Opin Biol Ther. Emerging role of monoclonal antibodies in the treatment of IgA nephropathy

[2] Mohit Mathur, et al. Kidney Int Rep. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers

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Keywords: Sibeprenlimab, VIS649 supplier, inhibitors, activators

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