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SHP389

Cat. No. M10887

All AbMole products are for research use only, cannot be used for human consumption.

SHP389  Structure

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Quality Control & Documentation
Biological Activity

SHP389 is an allosteric inhibitor of SHP2, which is anti-SHP2 and p-ERK IC50 The values are all 36 nM.

Chemical Information
Molecular Weight 484.98
Formula C23H29ClN8O2
CAS Number 2235394-90-6
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jeffrey T Bagdanoff, et al. J Med Chem. Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

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Keywords: SHP389 supplier, inhibitors, activators

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