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Serclutamab talirine

Cat. No. M24944

All AbMole products are for research use only, cannot be used for human consumption.

Serclutamab talirine Structure
Synonym:

ABBV-321

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Quality Control & Documentation
Biological Activity

Serclutamab talirine (ABBV-321) is an EGFR-targeted antibody-drug conjugate (ADC). Serclutamab talirine is consisted of an antibody (AM-1-ABT-806) directed against activated EGFR and a pyrrolobenzodiazepine (PBD) dimer. Serclutamab talirine shows potent antitumor activity.

Chemical Information
CAS Number 2140174-56-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Benedito A Carneiro, et al. Neurooncol Adv. Phase I study of anti-epidermal growth factor receptor antibody-drυg conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma

[2] Kendra A Porath, et al. Neurooncol Adv. Convection enhanced delivery of EGFR targeting antibody-drυg conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts

[3] Mark G Anderson, et al. Mol Cancer Ther. Targeting Multiple EGFR-expressing Tumors with a Highly Potent Tumor-selective Antibody-Drυg Conjugate

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  Catalog
Abmole Inhibitor Catalog




Keywords: Serclutamab talirine, ABBV-321 supplier, Drug-Linker Conjugates for ADC, inhibitors, activators

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