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Seclidemstat (SP-2577) mesylate is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor (Ki=31 nM, IC50=13 nM). Seclidemstat mesylate promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate can be used for the research of Ewing Sarcoma.
| Molecular Weight | 547.04 |
| CAS Number | 2044953-70-8 |
| Solubility (25°C) | DMSO 53.33 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
| Related Histone demethylase Products |
|---|
| PFI-90
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. |
| CPI-4203
CPI-4203 is a potent KDM5A inhibitor with an IC50 of 250 nM. |
| KDM2B-IN-4
KDM2B-IN-4 is a histone demethylase KDM2B inhibitor. |
| Zavondemstat
Zavondemstat (QC8222; TACH 101) is an inhibitor of histone lysine demethylase 4D (KDM4D) with antineoplastic activity. |
| Zavondemstat L-lysine
Zavondemstat (QC8222; TACH 101) (L-lysine) is an inhibitor of histone lysine demethylase 4D (KDM4D) with antineoplastic activity. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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