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SecinH3

Cat. No. M20608

All AbMole products are for research use only, cannot be used for human consumption.

SecinH3 Structure

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Quality Control & Documentation
Biological Activity

SecinH3 is a selective cytohesin inhibitor with IC50 of 2.4 μM, 5.4 μM, 5.4 μM, 5.6 μM, 5.6 μM, and 65 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, and yGea2-S7, respectively.

Chemical Information
Molecular Weight 460.50
Formula C24H20N4O4S
CAS Number 853625-60-2
Solubility (25°C) DMSO 92 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yimin Dong, et al. Pharmacol Res. Blocking the cytohesin-2/ARF1 axis by SecinH3 ameliorates osteoclast-induced bone loss via attenuating JNK-mediated IRE1 endoribonuclease activity

[2] Chenyang Yi, et al. Cell Rep. Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection

[3] Vahitha B Abdul-Salam, et al. Circ Res. CLIC4/Arf6 Pathway

[4] Wentao Hu, et al. IUBMB Life. SecinH3 Attenuates TDP-43 p.Q331K-Induced Neuronal Toxicity by Suppressing Endoplasmic Reticulum Stress and Enhancing Autophagic Flux

[5] Feng Guo, et al. Asian Pac J Trop Med. Effect of SecinH3 on lung injury induced by sepsis of rats

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  Catalog
Abmole Inhibitor Catalog




Keywords: SecinH3 supplier, inhibitors, activators

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